
Parathyroid Hormone (1-34), bovine
CAS No. 12583-68-5
Parathyroid Hormone (1-34), bovine ( —— )
产品货号. M33742 CAS No. 12583-68-5
Parathyroid Hormone (1-34), bovine 是一种有效的甲状旁腺激素 (PTH) 受体激动剂。Parathyroid Hormone (1-34), bovine 增加钙和无机磷酸盐的水平。Parathyroid Hormone (1-34), bovine 可用于研究骨质疏松症。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥1150 | 有现货 |
![]() ![]() |
5MG | ¥1591 | 有现货 |
![]() ![]() |
10MG | ¥2398 | 有现货 |
![]() ![]() |
25MG | ¥3847 | 有现货 |
![]() ![]() |
50MG | ¥5607 | 有现货 |
![]() ![]() |
500MG | 获取报价 | 有现货 |
![]() ![]() |
1G | 获取报价 | 有现货 |
![]() ![]() |
生物学信息
-
产品名称Parathyroid Hormone (1-34), bovine
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Parathyroid Hormone (1-34), bovine 是一种有效的甲状旁腺激素 (PTH) 受体激动剂。Parathyroid Hormone (1-34), bovine 增加钙和无机磷酸盐的水平。Parathyroid Hormone (1-34), bovine 可用于研究骨质疏松症。
-
产品描述Parathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis.
-
体外实验Parathyroid Hormone (1-34), bovine (0.1-100 ng/mL; 2-20 days) are added to the medium, it inhibits osteoblast proliferation in a dose-dependent manner. In another group, bPTH are added to the culture medium from day 1 to day 10, but not from days 11 to 20, a rebound of proliferation is observed in the PTH Day 1–10 group after bPTH withdrawal.Parathyroid Hormone (1-34), bovine (0.1-100 ng/mL; 2-20 days) induces diverse effects on the calcium and phosphorus content of culture medium. The calcium and phosphorus content of culture medium in the PTH-C 100 ng/mL group are higher than in teh control group.Cell Proliferation Assay Cell Line: MC3T3-E1 cells Concentration:0.1-100 ng/mL Incubation Time:2-20 days Result:Resulted a decrease of osteoblast proliferationin concentration-dependent manner.
-
体内实验Parathyroid Hormone (1-34)(subcutaneous?injection; 80 μg/kg; 5 days) increases serum osteocalcin concentrations without changing serum inorganic phosphate or calcium concentrations in either group of old animals.?Serum 1,25-dihydroxyvitamin D concentrations are significantly higher in the PTH-treated senile female rats than the sex-matchedvehicle-treated controls.
-
同义词——
-
通路Endocrinology/Hormones
-
靶点THR
-
受体Thyroid hormone receptor(THR)
-
研究领域——
-
适应症——
化学信息
-
CAS Number12583-68-5
-
分子量4104.39
-
分子式C183H288N54O50S2
-
纯度>98% (HPLC)
-
溶解度In Vitro:?H2O 中的溶解度 : 50 mg/mL (12.17 mM; 超声助溶)
-
SMILES——
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. B H Mitlak, et al. Intermittent administration of bovine PTH-(1-34) increases serum 1,25-dihydroxyvitamin D concentrations and spinal bone density in senile (23 month) rats. J Bone Miner Res. 1992 May;7(5):479-84.?
产品手册




关联产品
-
DS08210767
DS08210767 是一种高效的,具有生物口服可利用 PTHR1 拮抗剂,IC50 值为 90 nM。
-
MB-07811
MB-07811 是 MB07344 的口服活性 HepDirect 前药,具有降低胆固醇和甘油三酯的活性。 MB-07811 是一种肝脏靶向 THR-β 的激动剂。
-
Methimazole
甲硫咪唑(他巴唑,Northyx)是一种抗甲状腺化合物。